Design and Check the peptide efficacy before synthesis and trial. We seek to leverage our proprietary computational peptide drug design platform to produce novel, pre-clinical peptide drug candidates for diverse protein targets.
1. Design the Peptide
Reference peptide sequence from the User
(or)
Find a Peptide from the lead protein
Proteins are large molecule which contains 1000 of amino acids, from which small range of peptide is restricted, which mimics or exhibits or demonstrates the protein activity.
2 . Peptide modification
Like Cyclic and Cross links Peptide we do all type of modification in peptide.
Length of the peptide from 20aa to 200aa.
3. Study the Peptide Activity
Through interaction study of lead protein with target protein, amino acid responsible for activity can be found, by which peptide can be constrained.
4. Restriction
5. Investigation
Cross checking the activity of lead peptide with parental protein to ensure that the lead peptide mimics/impersonates the parental protein.
6. Validation
To check the stability of peptide
To check the stability of peptide with target protein
7. Molecular Dynamics
Validation for peptide.
Validation for peptide with target protein.
8. Why MD ?
Does it retain the structure in both protein & peptide after molecular dynamics study?
Does the protein and peptide split after dynamics study?
Does they maintain bond length?
MD Simulation and Annealing
Peptide for further Research / Synthesis
Priveel Custom Peptides
RMZ Milenia Business Park,
Phase 2, Campus 3B,
Dr. M.G.R Road, Kadanchavady,
Chennai, Tamil Nadu 600096
+91 9123531574
getinfo@priveelpeptides.com
